Sciatica refers to irritation or impingement of the sciatic nerve – a large nerve originating in the low back and made up of several nerve roots coming off of the spinal cord. For some people, the pain caused by irritation of these sciatic nerves can be almost unbearable – with little or no relief. What Causes Sciatica? Sciatica nerve pain is caused by pressure on the sciatic nerve – a very large nerve that originates from the lower lumbar spine and travels through the buttock into the ...

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